Chunyan Li's Website

Research

I work at the intersection of applied mathematics, scientific machine learning, and biomedical modeling. My research develops structure-aware methods for predictive digital twins: models that combine mechanistic knowledge, data-driven learning, and reliable computation to infer individualized dynamics from multimodal data and support scientific prediction and decision-making.

Across applications, I integrate partial differential equations, physical laws such as energy dissipation and mass conservation, numerical analysis, physiological and pathological mechanisms, and uncertainty-aware inference. My long-term goal is to develop efficient, trustworthy, and interpretable digital twins for health.

Future Goals

My future research will advance hybrid digital twins for health through uncertainty-aware inference, structure-constrained discovery of unknown mechanisms, and fast operator-learning surrogates. In parallel, I will develop scalable and structure-preserving neural solvers for multiscale PDEs. Together, these directions aim to connect rigorous applied mathematics with consequential problems in health, medicine, and scientific computing.

Community Activities